Player Bio
| HT/WT: 6-4, 263 lbs |
| Birthplace: Athens, GR |
| Age: 25 |
| School: Purdue |
| Experience: 5 |
Next Game
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1:07High Expectations for Chiefs OT Josh Simmons
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9:22Breaking Down the AFC West Offseason Checklist
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9:39JP Acosta Breaks Down 2026's Instant Impact Rookies
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1:16Chiefs' 2026 Instant Impact Rookie: R. Mason Thomas
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1:46Who They Should Take NFL Mock Draft: Kansas City At No. 9
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1:30NFL Trade Deadline: Biggest Names Who Could Be on the Move
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8:45Can anyone stop Caleb Williams and the Chicago Bears? | Set, Hut!
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1:37NFL Week 9 Picks: Broncos at Panthers
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1:47NFL Week 9 Picks: Jets at Chiefs
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0:53Should the Broncos Trade for Jonathan Taylor?
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1:22JP's Playbook: Broncos Rookie RB Jonah Coleman
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1:22How Caleb Williams, Bears Owned Seahawks Defense
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1:52Bears Neutralize Seahawks Passing Attack
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1:32Brandon Aiyuk Hires Agent, Seeks Return to NFL
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1:54NFL Trade Prediction: George Pickens to the Chiefs
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1:28Stock Up: Jonah Coleman Shines in Broncos' Week 8 Win
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1:54Trade Deadline Rumors Heat Up for Broncos and Chiefs
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1:56AFC West Pick: Chiefs or Broncos?
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0:30Brittany Mahomes Reacts to Controversial Call
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1:56NFC Playoff Picture Following Sunday
2026 Defensive
| STATS |
CMB
Total Tackles
|
SCK
Sacks
|
FUM
Forced Fumbles
|
INT
Interceptions
|
TD
Interceptions Returned For Touchdown
|
|---|---|---|---|---|---|
| Regular Season | 26 | 2.0 | 1 | 1 | 0 |
Top George Karlaftis News
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Chiefs' George Karlaftis: Notches first sack of 2026
Karlaftis registered six total tackles, a sack and two pass breakups in Sunday's 22-6 win over the Chargers.
Though Sunday's contest marked the first time all season that he notched a sack, Karlaftis has been making life difficult on quarterbacks throughout the campaign. Per Pro Football Focus, Karlaftis ranks seventh in the NFL with 27 total quarterback pressures, including 19 over the Chiefs' past two games. Karlaftis has also tallied 21 tackles, four pass breakups and an interception through five appearances.
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Chiefs' George Karlaftis: Played through broken hand in 2025
Defensive line coach Joe Cullen said Wednesday that Karlaftis played multiple games with a broken hand in 2025, Pete Sweeney of The Kansas City Star reports.
Despite the serious injury he apparently sustained prior to Week 11 at Denver, Karlaftis missed only one game last season, sitting out in Week 18 when the Chiefs were already eliminated from playoff contention. Now fully healthy, he projects to again play a huge role on the edge for Kansas City in 2026.
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Chiefs' George Karlaftis: Posts career-high stops in 2025
Karlaftis accumulated 48 tackles (25 solo), including 6.0 sacks, two pass defenses and one fumble recovery across 16 games in 2025 with the Chiefs.
The fourth-year pro looked like he was on his way to a career year after opening the season with 4.5 sacks and 20 combined tackles through the first five games of the regular season. Karlaftis wasn't able to carry that momentum for the rest of 2025, but his combined tackles were one more than his previous career high set in 2023 (across 16 regular-season games). The 2022 first-rounder signed a four-year, $93 million contract extension in July and will be a cornerstone of the Chiefs' defense for years to come.
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Chiefs' George Karlaftis: Unavailable for Week 18
Karlaftis (rest) is inactive for Sunday's contest against the Raiders, Matt McMullen of the Chiefs' official site reports.
Karlaftis will get a breather in the regular-season finale with Kansas City already eliminated from the postseason. In his absence, Charles Omenihu is a top candidate to take over as a starter on the defensive line versus Las Vegas.
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Chiefs' George Karlaftis: Questionable yet healthy
Karlaftis (rest) is listed as questionable ahead of Sunday's game against the Raiders.
Karlaftis was a limited participant throughout Week 18, but his injury status is listed as non-injured rest. The defensive end signed a four-year, $93 million contract with the Chiefs in July. The team may just be looking to protect a valuable asset ahead of the 2026 season, as Kansas City missed the playoffs for the first time since the 2014 campaign. If Karlaftis is inactive for Sunday's game, he will end the season with 48 tackles (25 solo), including 6.0 sacks, and two passes defensed through 16 games.
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