The NFL playoff picture comes further into focus with each passing week and the Week 17 NFL schedule should provide more definitive answers on who will be in the postseason and who won't. The Philadelphia Eagles had a chance to clinch the NFC East against the Washington Commanders last week but couldn't get the job done. Now, they'll have another chance to clinch with a win over the Dallas Cowboys on Sunday, but will be without starting quarterback Jalen Hurts (concussion), while the Cowboys will be without receiver CeeDee Lamb (shoulder). The latest Week 17 NFL odds list the Eagles as 7.5-point favorites, while the Commanders are 3.5-point favorites to clinch an NFC Wild Card spot against the NFC South-leading Falcons.
Who should you back in that game and how should you handle all your NFL money line, NFL over-under and NFL against the spread spread picks? Before you make any Week 17 NFL picks and Week 17 NFL score predictions, you need to see the NFL against the spread, NFL over-under, and NFL money line predictions powered by the self-learning SportsLine AI.
Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team's historical data and then quantitatively evaluating the strength of the opponent's defense by assigning a numeric value out of 100 called a matchup score.
Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see an A-rating on an over bet if a team is facing a poor defense, their prediction differs from the line and there are favorable odds.
In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. SportsLine's AI PickBot has hit a whopping 2,131 4.5- and 5-star prop picks since the start of last season. Anyone who has followed it is way up at their best sports betting app and favorite betting sites.
For Week 17 NFL betting, the AI PickBot has evaluated the NFL odds and provided NFL betting picks for all 16 games. You can only see the AI predictions for the Week 17 NFL schedule here.
Top Week 17 NFL AI picks
After analyzing every game in Week 17, the AI PickBot says the Browns cover comfortably as 3.5-point home underdogs against the Dolphins on Sunday. Miami kept slim playoff hopes alive with a win over the 49ers last week but no longer has control of its own fate in the AFC playoff picture.
Oddly enough, it's been the Miami offense that has struggled this season. The Dolphins ranked second in the NFL in scoring and first in total offense last season, but enter Week 17 ranked 23rd in scoring and 18th in total offense in 2024. Meanwhile, the Cleveland defense has actually been playing decently the last few weeks despite having to paper over the fact that the offense has turned the ball over at least three times in five straight games. Dolphins quarterback Tua Tagovailoa is doubtful with a hip injury, while receiver Jaylen Waddle (knee) is questionable.
The Browns are only allowing 301.3 yards per game over the last three weeks and Myles Garrett has eight sacks over his last seven games. That's a big reason why the AI PickBot rates a Browns cover as an A+ pick and also predicts a 27-22 outright win on average. See its other Week 17 football predictions and football picks at SportsLine.
How to make Week 17 NFL picks
In addition, the AI PickBot has generated 13 more highly-coveted A+ picks for Week 17. You need to see the AI PickBot's NFL picks before making any Week 16 NFL bets of your own. You can only see them at SportsLine.
Who wins and covers each Week 17 NFL game, and which A+ picks should you target now? Visit SportsLine now to see the top NFL picks against the spread, over-under, and on money line, all from the self-learning SportsLine AI PickBot that has nailed 2,131 top-rated picks since the start of last season.