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It's a rematch of the Africa Cup of Nations final on Friday when Egypt hosts Senegal in the first leg of their third-round matchup in Africa's 2022 FIFA World Cup Qualifying. It will also pit Liverpool teammates Mohamed Salah of Egypt and Senegal's Sadio Mane against each other again. The Senegalese got the best of the Pharaohs in last month's championship game, prevailing 4-2 on penalty kicks. Both teams failed to score in 120 minutes, and they could stick to a defensive game Friday at Cairo International Stadium in anticipation of the rematch next Tuesday in Dakar.

Kickoff is set for 3:30 p.m. ET in Cairo, Egypt. Caesars Sportsbook lists Egypt as the +145 favorite (risk $100 to win $145) on the 90-minute money line in its latest Egypt vs. Senegal odds, with Senegal the +215underdog. A draw is priced at +150 and the over-under for total goals scored is 1.5. Before locking in any Senegal vs. Egypt picks or 2022 FIFA World Cup Qualifying predictions, you need to see what international soccer insider Jon Eimer has to say

Eimer is a high-volume bettor who has vast knowledge of leagues and players across the globe. Since joining SportsLine, Eimer has covered the English Premier League, Serie A, the FA Cup and much more. The Indiana-based handicapper compiled a winning record of 260-133-1 with over 90 units of profit for his community on various platforms over a recent two-month stretch. He is 8-3 on his World Cup Qualifying picks since his debut.

Now, Eimer has taken a close look at the Egypt vs. Senegal matchup and released his picks and predictions. You can head to SportsLine now to see Eimer's picks. Here are the betting lines and trends for Senegal vs. Egypt:  

  • Egypt vs. Senegal spread: Egypt -0.5 (+160)
  • Egypt vs. Senegal over-under: 1.5 goals
  • Egypt vs. Senegal money line: Egypt +145, Senegal +215, Draw +150
  • Egypt: Omar Marmoush has three goals and four assists with Stuttgart in Bundesliga
  • Senegal: Ismaila Sarr has 23 goals the past three seasons with Watford in the EPL

Why you should back Egypt

The Pharaohs will be out for revenge after the heartbreaking defeat last month kept them from adding to their record seven AFCON titles. Salah will be the best player on the field Friday, and he is due for a breakthrough. The English Premier League's leading scorer with 20 goals has yet to find the net in his five qualifying matches. But he also has 10 assists in EPL play, tied for second in the league, and has set up three goals for his teammates so far in qualifying.

Magdi Afsha and Mostafa Mohamed each have scored twice, playing seven games between them. Five other players have scored once, with Omar Marmoush producing a goal and an assist. Afsha also had two goals and three assists at AFCON, while Mohamed has 14 goals over the past two seasons with Galatasaray in Turkey's Super Ligue. 

Why you should back Senegal

Senegal is one of the best all-around teams in the African qualifying tournament, and it scored 15 goals in six matches in the second round. It has many more options than the Egyptians, with Famara Diedhiou (four goals), Ismaila Sarr (three) and Mane (three) all capable of unlocking the defense. Mane has 12 goals in the EPL with Liverpool, Diedhiou has nine for Alanyaspor in the Turkish Super Ligue and Sarr has five in 15 starts for Watford in the English Premier League.

The Lions also are very tough to score on, as they boast one of the world's best goalkeepers. Edoaurd Mendy was the FIFA Goalkeeper of the Year in 2021 and helped Chelsea to the Champions League title. He has 11 clean sheets this season and is second in the EPL in save percentage (82.1). Senegal yielded just four goals in the second round, and it had a 13-7 advantage in shots in the AFCON final, putting eight on net to three for the Egyptians.

How to make Senegal vs. Egypt picks

Eimer has scrutinized Friday's Senegal vs. Egypt match from all angles, and he is leaning over on the goal total. He has two other confident best bets, both bringing plus money, and a full breakdown of the match. He's only sharing those World Cup Qualifying picks at SportsLine.

So who wins Egypt vs. Senegal? And where does all the betting value lie? Visit SportsLine now to see the best bets for Senegal vs. Egypt, all from the expert who is way up on his soccer picks, and find out.