Offensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Quarterback | B. MayfieldBaker Mayfield | K. TraskKyle Trask | |
| Running Back | B. IrvingBucky Irving | R. WhiteRachaad White | |
| Wide Receiver | M. EvansMike Evans | J. McMillanJalen McMillan | |
| Tight End | C. OttonCade Otton | P. DurhamPayne Durham | |
| Left Tackle | T. WirfsTristan Wirfs | J. SkuleJustin Skule | |
| Center | G. BartonGraham Barton | R. HainseyRobert Hainsey | — |
| Right Tackle | C. MauchCody Mauch | J. SkuleJustin Skule |
Defensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Left Defensive End | C. KanceyCalijah Kancey | — | — |
| Nose Tackle | V. VeaVita Vea | G. GainesGreg Gaines | |
| Right Defensive End | L. HallLogan Hall | W. GholstonWilliam Gholston | — |
| Left Inside Linebacker | K. BrittK.J. Britt | S. DennisSirVocea Dennis | — |
| Right Inside Linebacker | L. DavidLavonte David | J. RussellJJ Russell | |
| Strongside Linebacker | J. Tryon-ShoyinkaJoe Tryon-Shoyinka | S. BarrettShaquil Barrett | |
| Weakside Linebacker | Y. DiabyYaYa Diaby | A. NelsonAnthony Nelson | |
| Right Cornerback | Z. McCollumZyon McCollum | B. HallBryce Hall | |
| Left Cornerback | J. DeanJamel Dean | J. HayesJosh Hayes | |
| Slot Cornerback | T. SmithTykee Smith | T. ThomasTavierre Thomas | |
| Strong Safety | M. EdwardsMike Edwards | J. WhiteheadJordan Whitehead | |
| Free Safety | A. Winfield Jr.Antoine Winfield Jr. | K. MerriweatherKaevon Merriweather | — |
Special Teams Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Punter | J. BrowningJack Browning | — | — |
| Kicker | C. McLaughlinChase McLaughlin | — | — |
| Long Snapper | E. DeckersEvan Deckers | — | — |
| Holder | J. BrowningJack Browning | — | — |
| Punt Returner | T. PalmerTrey Palmer | J. McMillanJalen McMillan | |
| Kick Returner | S. TuckerSean Tucker | R. JarrettRakim Jarrett |