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San Francisco • #49 • RB

Isaac Guerendo

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NFC West Standings

Team Div Overall
LAR
 4-2-0 10-7-0
SEA
 4-2-0 10-7-0
ARI
 3-3-0 8-9-0
SF
 1-5-0 6-11-0
Full Standings
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2024 Rushing

STATS ATT
Rushing Attempts
YDS
Rushing Yards
AVG
Average Yards per Rush
TD
Rushing Touchdowns
LNG
Longest Rush
FL
Fumbles Lost
Regular Season 84 420 5.0 4 76 0
Full Career Stats

Top Isaac Guerendo News

  • 49ers' Isaac Guerendo: Has MCL, ankle sprains

    Rotowire

    Guerendo has been diagnosed with MCL and ankle sprains in his left leg following an MRI on Monday, Matt Barrows of The Athletic reports.

    The 49ers' 2024 campaign is over, but the team's season finale included yet another RB injury. On only his second carry of Sunday's game, Guerendo had his left leg twisted under him as he was tackled, and he needed a cart to go to the locker room. While Guerendo did avoid a more serious ACL injury, he's still one of four San Francisco running backs who will enter the offseason focusing on rehab, along with Christian McCaffrey (knee), Jordan Mason (ankle) and Elijah Mitchell (hamstring). Guerendo, a 2024 fourth-round pick, proved to be effective when given the chance as a rookie, turning 84 carries into 420 yards (5.0 YPC) and four touchdowns and hauling in 15 of 16 targets for 152 yards in 16 appearances.

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  • 49ers' Isaac Guerendo: MCL sprain likely, tests upcoming

    Rotowire

    Coach Kyle Shanahan said after Sunday's 47-24 loss to the Cardinals that Guerendo (knee/ankle) likely suffered an MCL sprain and will undergo further testing Monday, Lindsey Pallares of the 49ers' official site reports.

    Guerendo suffered knee and ankle injuries, with the knee injury likely to be an MCL sprain. The results of Monday's tests should help provide clarity on the recovery timeline for Guerendo. The 49ers' season came to a close with Sunday's defeat in the regular-season finale.

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  • 49ers' Isaac Guerendo: Won't return Sunday

    Rotowire

    Guerendo won't return to Sunday's game at Arizona due to knee and ankle injuries.

    Guerendo had his left leg twisted under him on his second carry of the game, and his teammates quickly motioned to the sideline for assistance. He eventually was carted off the field and ruled out not long after. With Guerendo unavailable, the 49ers will entrust the run game in Patrick Taylor and FB Kyle Juszczyk for the rest of their season finale.

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  • 49ers' Isaac Guerendo: Nets 99 yards in return

    Rotowire

    Guerendo took nine carries for 34 yards while bringing in all four targets for 65 yards in Monday's 40-34 loss to the Lions.

    Guerendo made a successful return from a one-game layoff due to foot and hamstring injuries Week 17. The fourth-round rookie looked no worse for wear, generating 99 yards from scrimmage in a pass-heavy game plan. The only negative aspect of Guerendo's fantasy line was a lack of trips to the end zone after quarterbacks Brock Purdy (elbow) and Joshua Dobbs vultured a pair of short touchdown rushes. Guerendo may find himself more involved as a rusher if San Francisco's injured starting QB is unable to suit up against the Cardinals on Sunday.

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Player Bio

HT/WT: 6-0, 221 lbs
Birthplace: Clayton, IN
Age: 24
School: Louisville
Experience: 2