The Atlanta Falcons are off to a 2-0 start heading into a Week 3 matchup against the Detroit Lions on Sunday. These two up-and-comers in the NFC will now look for a critical early-season win. Kickoff is scheduled for 1 p.m. ET and the Lions are three-point favorites in the Week 3 NFL odds from the SportsLine Consensus. Both teams are 1-1 against the spread this season, so which side should you back as you place your NFL bets and put together your Week 3 NFL parlays? Moneyline underdog parlays have had the potential to be profitable this season with 14 underdogs winning outright over the first two weeks, so which teams are most likely to be Week 3 NFL upset picks?

The Bears are 12.5-point dogs and getting a whopping +532 on the moneyline if you think they can pull out of their funk to upset the Chiefs, who have already lost to one NFC North team (Detroit) as favorites this season. Before you make any Week 3 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine's proven computer model.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 3 of the 2023 NFL season on an incredible 164-117 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 18-9 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 3. If you successfully parlay its picks, you'd be looking at a massive payout of around 25-1. You can only see the model's Week 3 NFL picks at SportsLine.

Top Week 3 NFL picks

After simulating every game 10,000 times, the model is high on the Baltimore Ravens (-8) to cover at home against the Indianapolis Colts. Baltimore is one of only two teams in the AFC to enjoy a 2-0 start (along with Miami) after beating the Texans 25-9 in Week 1 and then defeating the Bengals 27-24 on the road as three-point underdogs in Week 2.

The Ravens rank top 12 in the NFL in total offense, scoring offense, total defense and scoring defense through the first two weeks of the season. Their play in the red zone has also been a major catalyst for their success, as the Ravens have scored touchdowns on six of nine trips inside the 20-yard line (seventh in the NFL) while only allowing touchdowns on two of their opponents' six trips (third) into the scoring area.

Meanwhile, Colts quarterback Anthony Richardson remains in concussion protocol and is in serious jeopardy of missing Week 3. Gardner Minshew is among the league's more capable backups, but the Indianapolis running game in particular could suffer without Richardson's dynamic athletic ability. That's a big reason why the model has Baltimore covering the spread in over 60% of simulations. See which other NFL parlay picks to make here.

How to make Week 3 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including three favorites who cover with points to spare. You can only see the model's NFL Week 3 best bets and parlay at SportsLine. 

What are the model's top Week 3 NFL picks? And which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 3 NFL best bets from a model on a 164-117 run on top-rated picks, and find out.