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Aaron Rodgers and the Green Bay Packers will fight for a spot in the postseason when they host the Detroit Lions on Sunday Night Football. It's been a bumpy road for the Packers this year, but the team has gelled and is on a four-game winning streak. Green Bay's rookie receivers, particularly Christian Watson, have given Rodgers enough fuel to keep the team's hopes afloat. All they now need to do is beat the Lions on SNF. Detroit is also still alive in the NFL playoff picture, but the Lions will need the Seahawks to lose earlier in the day if they're to have a shot. Expect the Lions to come out with their hair on fire if Seattle is upset by the Rams. The Packers are five-point favorites in the latest Week 18 NFL odds at Caesars Sportsbook. Which Week 18 NFL lines should you target with your Week 18 NFL bets? Before you make any Week 18 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine's proven computer model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 18 of the 2022 NFL season on an incredible 160-113 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 14-6 roll on top-rated NFL picks since Week 7 of this season.  

The model ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 18. If you successfully parlay its picks, you'd be looking at a massive payout of around 25-1. You can only see the model's Week 18 NFL picks at SportsLine.

Top Week 18 NFL picks

After simulating every game 10,000 times, the model is high on the Seattle Seahawks (-6.5) to cover against the Los Angeles Rams. Baker Mayfield has looked reinvigorated since landing at SoFi Stadium, but the Rams have nothing to play for on Sunday and will still be without a number of key players. That will hamstring them playing on the road in Seattle against a Seahawks team that's hungry for the playoffs.

Seattle will get in if they beat the Rams and the Lions subsequently beat the Packers. The Seahawks can only hold up their end of the bargain, but that's more than enough motivation for Pete Carroll's team. That is one reason the Seahawks are covering the spread in more than 50% of simulations. See which other NFL parlay picks to make here.

How to make Week 18 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including a pair of underdogs that have a chance to win outright. You can only see the model's NFL Week 18 best bets and parlay at SportsLine

What are the model's top Week 18 NFL picks? And which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 18 NFL best bets from a model on a 160-113 run on its top-rated picks, and find out.