Seven teams can clinch a spot in the NFL playoff picture when Week 15 resumes on Sunday. The Patriots, Titans, Cardinals, Cowboys, Packers, Rams and Buccaneers all can clinch a spot in the postseason. Tennessee, Dallas, Green Bay and Tampa Bay can clinch divisional titles. No team is a bigger favorite in Week 15 than Arizona, which is tied for the best record (10-3) in the league and faces the team, Detroit (1-11-1), with the worst. Arizona is a 12.5-point favorite in the latest NFL odds from Caesars Sportsbook, but which side should you back with your NFL bets and NFL parlays?

The game is one of 16 on a full Week 15 NFL schedule. Other key matchups include the Packers and Ravens battling in Baltimore and the Buccaneers hosting the Saints on Sunday Night Football. Before locking in any Week 15 NFL picks on those games or others, be sure to see the NFL predictions and betting advice from SportsLine's proven computer model.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 15 of the 2021 season on an incredible 132-96 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 15. If you successfully parlay its picks, you'd be looking at a massive payout of 25-1. You can only see the model's Week 15 NFL picks at SportsLine

Top Week 15 NFL picks

After simulating every game 10,000 times, the model is high on the Saints to cover as 11-point underdogs on the road against the Tampa Bay Buccaneers. The Saints (6-7), who have reached the playoffs for four consecutive seasons, badly need a late-season push to reach their fifth straight postseason. They entered the week No. 11 in the NFC standings. Meanwhile, the Buccaneers (10-3) are looking for their first divisional title since the 2007 season.

New Orleans faces a Tampa Bay secondary that has been ravaged by injuries. On Thursday, safety Antoine Winfield and cornerbacks Jamel Dean or Richard Sherman didn't practice, and safety Jordan Whitehead has missed the last two games with a calf injury and is still trying to work his way back.

How to make Week 15 NFL parlays

The model also jumped on four other matchups where it says the line is way off, including a divisional battle and a game between two teams fighting for their playoff lives. You can only see the model's NFL Week 15 best bets and parlay at SportsLine

What are the model's top Week 15 NFL picks? And which other NFL matchups should you target for a 25-1 payout? Visit SportsLine now to see the Week 15 NFL best bets from a model on a 132-96 run on its top-rated picks, and find out.