NFL bettors have a data point for every team in the league heading into the Week 2 NFL schedule, so it can be tempting to make bold Week 2 NFL score predictions. Cincinnati was an 8.5-point favorite in its loss to New England last week and has a tricky matchup against Kansas City on Sunday. The Bengals are six-point road underdogs in the Week 2 NFL odds, even though they are the last team to beat the Chiefs in the postseason. All four meetings between Patrick Mahomes and Joe Burrow have been decided by a field goal, so should you back the Bengals with your Week 2 NFL bets?
Other NFL games today include Cowboys (-6) vs. Saints, Cardinals (-1) vs. Rams, and Texans (-6.5) vs. Bears. Which Week 2 NFL spreads have the most value in the NFL odds this week? Before you make any Week 2 NFL picks, you need to see the NFL against the spread, over-under, and money line predictions powered by SportsLine AI.
Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team's historical data and then quantitatively evaluating the strength of the opponent's defense by assigning a numeric value out of 100 called a matchup score.
Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see an A-rating on an over bet if a team is facing a poor defense, their prediction differs from the line and there are favorable odds.
In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. Last season, SportsLine's AI PickBot hit a whopping 1,674 4.5- and 5-star prop picks. Anyone who has followed it is way up.
For Week 2, the AI PickBot has evaluated the NFL odds and provided NFL predictions for all 16 games. You can only see the AI predictions for the Week 2 NFL schedule here.
Top Week 2 NFL AI picks
After analyzing every game in Week 2, the AI PickBot says the Jaguars cover as three-point favorites at home against the Browns. A pair of former Clemson quarterbacks will be on the field in this matchup, but bettors could feel better about backing Trevor Lawrence than Deshaun Watson. Lawrence was strong early last season and is coming off a steady showing against Miami, while Watson threw for just 169 yards with two interceptions in a blowout loss to Dallas.
Watson was 0-for-10 passing on throws that traveled at least 15 yards through the air, with his 2.2 yards per attempt being the second lowest by any quarterback in a game in the last 10 seasons (minimum of 20 attempts). The Browns went 3-6 in nine road games last season and have only covered the spread once in their last five games against Jacksonville. Meanwhile, the Jaguars have covered in four of their last six September games. The AI PickBot has them winning this game by five points on average. See its other Week 2 football predictions and football picks at SportsLine.
How to make Week 2 NFL picks
In addition, the AI PickBot has generated five A-rated picks for Week 2. You need to see the AI PickBot's picks before making any Week 1 NFL bets of your own. You can only see it at SportsLine.
Who wins and covers each Week 2 NFL game, and which A-rated picks should you target? Visit SportsLine now to see the top NFL picks against the spread, over-under, and on money line, all from the brand-new SportsLine AI PickBot that nailed 1,674 top-rated picks last season.
