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Momentum can carry over from week-to-week during an NFL season, but what about from year-to-year? The Chicago Bears finished 2023 with a 5-2 record against the spread (71.4%) after posting a cover rate of just 32.6% over their previous 44 games, dating back to 2021. They'll match up with a Titans team during the Week 1 NFL schedule that went just 4-9 against the spread to end the 2023 season. The Bears have a new quarterback, Caleb Williams, while the Titans have a new coach, Brian Callahan. Chicago is favored by 3.5 points in the Week 1 NFL lines, and only Terry Bradshaw (-5, 1970) was a larger favorite in Week 1 as a rookie quarterback than Williams is. So, should how 2023 ended play a factor when evaluating the NFL odds for Sunday? Before you make any Week 1 NFL picks, you need to see the NFL against the spread, over-under, and money line predictions powered by SportsLine AI.

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine's Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team's historical data and then quantitatively evaluating the strength of the opponent's defense by assigning a numeric value out of 100 called a matchup score. 

Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see an A-rating on an over bet if a team is facing a poor defense, their prediction differs from the line and there are favorable odds.

In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. Last season, SportsLine's AI PickBot hit a whopping 1,674 4.5- and 5-star prop picks. Anyone who has followed it is way up.

For Week 1, the AI PickBot has evaluated the NFL odds and provided NFL predictions for all 16 games. You can only see the AI predictions for the Week 1 NFL schedule here.

Top Week 1 NFL AI picks

After analyzing every game in Week 1, the AI PickBot says the Broncos cover as six-point underdogs against the Seahawks in a game that has earned an A-rated pick. Seattle was just one of two NFL teams that failed to cover versus a non-conference foe last season, as it came up short ATS in all five games against AFC opponents. The Seahawks' woes as a favorite, however, extend beyond just last year. Since the start of the 2021 season, Seattle is just 8-14-2 (36.4%) against the spread as a favorite, and only four teams have worse records over that span.

Denver turned its season around after a 1-5 start in 2023 as it finished the year going 7-4. The defense was the catalyst, allowing 19.4 PPG, while the Broncos finished the season ranked among the top 10 in turnover differential. Having extra possessions will allow a Sean Payton-led offense to take advantage of a Seahawks defense which has allowed the most total ypg (366.5) over the last two seasons, ranking 25th in points allowed in each. With those factors, the AI PickBot forecasts this game to be much closer than the 6-point spread indicates, as it projects Seattle to win by just 1.52 points. See its other Week 1 football predictions and football picks at SportsLine.

How to make Week 1 NFL picks

In addition, the AI PickBot has generated eight more A-rated picks for Week 1. You need to see the AI PickBot's analysis before making any Week 1 NFL bets. You can only see it at SportsLine.

Who wins and covers each Week 1 NFL game, and which A-rated picks should you be targeting?  Visit SportsLine now to see the top NFL picks against the spread, over-under, and on money line, all from the brand-new SportsLine AI PickBot that nailed 1,674 top-rated picks last season.