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Pete Carroll and the Seattle Seahawks (9-8) will visit Kyle Shanahan and the San Francisco 49ers (13-4) in a 2023 NFL Super Wild Card game on Saturday. San Francisco swept the season series and will try to secure its third win in a row over Seattle. Meanwhile, Seattle is looking to advance to the divisional round of the NFL playoff bracket for the first time since 2019. The 49ers are 7-2 against the spread at home this season, while the Seahawks are 3-5 against the number on the road.

Kickoff is at 4:30 p.m. ET in San Francisco. Caesars Sportsbook lists the 49ers as a 9.5-point favorite, while the over/under, or total number of points Vegas thinks will be scored, is 42 in the latest Seahawks vs. 49ers odds. Before you make any 49ers vs. Seahawks picks and NFL predictions, you need to see what SportsLine's resident Seahawks expert, Josh Nagel, has to say.

Nagel is a Nevada-based handicapper with more than 20 years of experience in the sports wagering industry. SportsLine's assistant managing editor has covered the wagering industry on a variety of platforms and has won numerous sports handicapping contests. He has hit 54% of his NFL picks against the spread (749-636-22) since the start of the 2016 season.

In addition, Nagel has gone an incredible 21-8 in his last 29 spread picks involving the Seahawks. Anyone who has followed him is way up.

Now, Nagel has set his sights on Seahawks vs. 49ers and just locked in his picks and Super Wild Card NFL predictions. You can head to SportsLine now to see his picks. Now, here are several NFL odds and betting lines for Seahawks vs. 49ers:

  • Seahawks vs. 49ers spread: San Francisco -9.5
  • Seahawks vs. 49ers Over-Under: 42 points  
  • Seahawks vs. 49ers money line: San Francisco -475, Seattle +380 
  • SEA: Seahawks are 6-2 ATS in their last eight Wild Card games 
  • SF: 49ers are 8-0 ATS in their last 8 against NFC West opponents
  • Seahawks vs. 49ers picks: See picks here

Why the 49ers can cover

The 49ers have been stifling defensively and boast difference-makers all across the field. San Francisco was first in the league in total defense (300.6) and second in rushing yards allowed (77.7). They've allowed fewer than 70 rush yards in 10 games thus far. Linebacker Fred Warner is an instinctive and rangy defender in the middle of the field. Warner has strong play recognition skills, leading the team in total tackles (130) with 10 pass deflections.

The BYU product has finished with double-digit stops in two of his last three games. Defensive end Nick Bosa owns a superb repertoire of moves to wreak havoc in the backfield. Bosa explodes off the line and has the speed to get around tackles. The Ohio State product is first in the NFL in sacks (18.5) and tied for second in tackles for loss (19). He's recorded a sack in 13 of the 16 games he suited up for. See which team to pick here.

Why the Seahawks can cover

The Seahawks have been able to build an effective passing attack, finishing 12th in passing offense (231.4). Seattle had two receivers log more than 1,000 yards during the campaign. DK Metcalf is the leading pass-catcher and owns a unique combination of size (6-foot-4, 235 pounds) and quickness. The Ole Miss product leads the squad in receptions (90) and receiving yards (1,048) with six touchdowns.

Fellow receiver Tyler Lockett is a shifty route-runner who can get out his breaks in a hurry. Lockett has a knack for getting separation and creating huge plays. The Kansas State product has caught 14 passes of 20-plus yards. Lockett is second on the team with 84 catches for 1,033 yards and a team-high nine touchdowns. In his last outing, the 30-year-old snagged four catches for 54 yards and one score. See which team to pick here.

How to make Seahawks vs. 49ers picks

Nagel has analyzed this matchup and while we can tell you he's leaning Over the point total, he has discovered a critical X-factor that has him jumping all over one side of the spread. He's only sharing what it is, and which side to back, at SportsLine.

Who wins 49ers vs. Seahawks on NFL Super Wild Card Weekend 2023? And which critical X-factor makes one side of the spread a must-back? Visit SportsLine now to see which side of the 49ers vs. Seahawks spread to back, all from the expert who is an amazing 21-8 on Seahawks picks, and find out.