The final week of the 2024-25 NFL regular season has arrived, with the Week 18 NFL schedule bringing several games that have playoff seeding implications. Denver will try to clinch a playoff spot for the third week in a row when it hosts Kansas City in an AFC West matchup on Sunday. The Chiefs are resting several key players, so the Broncos are 11-point favorites in the Week 18 NFL odds, one of the largest Week 18 NFL spreads.
The biggest game of the week pits the Lions vs. Vikings on Sunday Night Football in a matchup that will decide the No. 1 seed in the NFC playoff bracket. Detroit is a 3-point favorite in the Week 18 NFL betting odds and picked up a road win at Minnesota earlier this season. Before locking in any Week 18 NFL picks or NFL prop bets, be sure to check out the Week 18 NFL best bets and predictions from SportsLine's red-hot Vegas experts.
SportsLine has more than 40 hand-picked Vegas experts who excel in multiple spots. The NFL, however, is a strength for the site as SportsLine currently has five total experts who are on NFL runs that have returned $1,800 or more for $100 players and three who have returned more than $2,200. Anybody following has seen huge returns.
Now, with the Week 18 NFL schedule quickly approaching, SportsLine's top NFL experts are already locking in their picks. Go to SportsLine to see them all now.
Top Week 18 NFL expert picks from Jason La Canfora
La Canfora has been covering the NFL since 2004 and spent 10 years as CBS's NFL Insider for "THE NFL TODAY" and across all platforms. He continues to cover the NFL as an analyst and insider for The Washington Post and gather information from a plethora of sources throughout the game. La Canfora is 29-16-2 in his last 47 NFL picks and has already locked in picks for multiple games throughout the weekend.
One bet that La Canfora has already placed is Over 48 points in Falcons vs. Panthers on Sunday. The Falcons and Panthers are a combined 9-1 in favor of the Over within the division this season, and Atlanta's offense has looked excellent with rookie quarterback Michael Penix Jr. at the helm. La Canfora is also high on a road team that he thinks will get revenge in a rematch against a divisional opponent. See all of La Canfora's picks here.
Top Week 18 expert NFL picks from Matt Severance
Severance is a well-connected writer and high-volume handicapper who has worked in the industry since 2005. After joining SportsLine, Matt quickly established himself as a top expert in multiple sports. He went 121-93-2 (plus $589) during the 2023 NFL season, and he is 34-10 (+1653) over his last 44 NFL ML picks.
He has already placed his bet for the Cardinals (-4.5, 43) vs. 49ers on Sunday. Arizona has lost five of its last six games, including a 13-9 road game against the Rams last week. San Francisco has dropped six of its last seven contests, and both teams have been eliminated from the playoff picture. Severance placed an early bet on this game because he believes one team has more motivation to win. See the rest of Severance's picks here.
Top Week 18 NFL expert picks from R.J. White
White is a Fantasy and gambling editor for CBS Sports, consistently crushing against-the-spread picks by going 643-543-34 on his ATS betting picks from 2017-23, which returned more than $4,600 to $100 players. He also went 101-84-4 (+1366) on all NFL spread picks last season. Additionally, White has been profitable betting NFL player props this season, going 19-12 (+600) in his last 31 picks.
He is backing the Buccaneers (-14, 44.5) to cover the spread against the Saints on Sunday. The Buccaneers are a win away from clinching the division title, while the Saints are out of the playoff conversation and are coming off two straight blowout losses. White has also locked in his pick for the Lions vs. Vikings in the biggest game of the week. See the rest of White's picks here.
Top Week 18 NFL expert picks from Mike Tierney
Tierney has covered the NFL for decades and reported from seven Super Bowls. He is 154-124-9 in the NFL the past two seasons, returning $1,586 to $100 players (every bet one unit). Tierney enters Week 18 on a 56-30-3 run in his last 89 NFL ATS bets (+2277).
The veteran sportswriter has already placed his bet on the Broncos (-11, 40.5) to cover against the Chiefs on Sunday. He got ahead of the early line movement by backing Denver in a game where Kansas City has no reason to compete. The Chiefs were blown out by the Raiders in a similar situation four years ago, and the Broncos need a win to clinch a playoff spot. Tierney is also backing a small favorite that needs a win to remain in the playoff hunt. You can find all of Tierney's picks here.
How to make Week 18 NFL against the spread picks
SportsLine's team of experts also includes Sia Nejad, a trial attorney turned analyst who is on a 57-33 run on NFL picks. He specializes in the NFL DFS and prop markets, and his dynamic approach to NFL betting is available only to SportsLine subscribers. This week, he's locked in a prop bet that has cashed in five of the last six games. Anyone who backs this player could hit it big. You can find out who his NFL picks are this weekend here.
If you are looking for NFL picks, NFL props, or NFL best bets for Week 18, SportsLine has you covered with its proven team of experts. Visit SportsLine now to see who which teams you should back in Week 18, all from a staff that includes five experts who are on NFL runs that have returned $1,800 or more for $100 players.