After 14 games on the Sunday NFL slate, the first week of the new season culminates with the Russell Wilson Bowl on Monday Night Football between his former team, the Seattle Seahawks and his new team, the Denver Broncos. That's 15 games left to choose in your first set of matchups for NFL confidence pool picks and NFL office pool picks. This week features several season-opening storylines, but which are the ones to pay attention to as you review the Week 1 NFL spreads and make your NFL football pool picks? Before you make your NFL predictions, you need to see the Week 1 NFL football pool picks from SportsLine's proven model.
The model, which simulates every NFL game 10,000 times, is up over $7,500 for $100 players on top-rated NFL picks since its inception. The model enters the 2022 NFL season on an incredible 138-97 run on top-rated NFL picks that dates back to the 2017 season.
More importantly for NFL confidence pool players, the model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94 percent of CBS Sports office pool players four times during that span. Anyone who has followed it is way up.
Now, the model has simulated the entire Week 1 NFL schedule 10,000 times and generated its optimal NFL pick'em plays. Go to SportsLine to see them now.
Top Week 1 NFL office pool predictions
One of the top Week 1 NFL predictions from the model: The Los Angeles Chargers (-3.5) open up their season with a six-point win at home against the Las Vegas Raiders. Last season, Raiders QB Derek Carr threw for 382 yards, four touchdowns and just one interception in two games against the Chargers, but he completed just 58.5 percent of his passes.
Even though anticipation is high for Davante Adams' potential with the Raiders, there is still uncertainty about how he'll look in his new digs after not playing in the preseason. Questions also surround Las Vegas tight end Darren Waller, who has been dealing with various issues that have largely kept him out of commission since Week 13 of last year. The Chargers gave up the sixth-fewest yards to opposing receivers in 2021, but they also gave up the most yards to tight ends.
Waller isn't on the Week 1 injury report for the Raiders, but the model predicts the Chargers will still hold him to just 60 receiving yards. Adams is projected to push for 90 receiving yards in his Raiders debut, but the model still picks Los Angeles to win by six in over 60 percent of all simulations. See the rest of the model's Week 1 NFL pool picks here.
How to make Week 1 NFL office pool picks
The model also made the call on every other Week 1 NFL game and has strong picks for potentially close matchups like Cowboys vs. Buccaneers and Vikings vs. Packers. It's also calling for one underdog to pull off an upset and several Super Bowl contenders to go down hard. You can only see all of the model's NFL pool picks here.
So who should you pick in every Week 1 NFL game? And which Super Bowl contenders go down? Visit SportsLine now to get optimal NFL office pool picks, all from the advanced computer model that has ranked in the top 10 on straight-up picks four of the last six years and went an outstanding 138-97 on top-ranked picks against the spread since 2017.