Injuries are opportunities in the NFL and both Jauan Jennings and Zach Charbonnet had their chances to show off their potential as key offensive pieces this season. Jennings had 11 receptions for 175 yards and three touchdowns against the Rams in Week 3 after generating more targets due to injuries to Deebo Samuel and George Kittle. Charbonnet had three touchdowns over two games Kenneth Walker missed due to injury and averaged 88 total yards per game. With Samuel and Walker healthy entering their Week 6 NFL Thursday Night Football matchup of 49ers vs. Seahawks, how should daily Fantasy football players view Jennings and Charbonnet when making NFL DFS lineups and NFL DFS stacks? Before locking in any NFL DFS lineups for Seahawks vs. 49ers on sites like DraftKings and FanDuel, be sure to check out the NFL DFS lineup advice, strategy and player stacks from SportsLine NFL daily Fantasy expert Jimmie Kaylor.
Kaylor is a NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor, who cashed big all season in 2022, has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks on sites like DraftKings and FanDuel.
Kaylor hit on epic NFL DFS picks for SportsLine members throughout the 2022 and 2023 seasons. In 2022, he was all over Travis Kelce's four-touchdown performance against the Raiders on Monday Night Football, Kirk Cousins' 460-yard, four-TD performance on Thanksgiving Day, and T.J. Hockenson's 13 catches for 109 yards and two touchdowns in Week 15. In 2023, he hit on Ja'Marr Chase's massive Week 5 performance (15 catches, 192 yards, three TDs), D.J. Moore's eight catches for 230 yards and three touchdowns in Week 14, and De'Von Anchane's breakout performance (233 total yards, four TD's) in Week 3. Anyone who followed his picks is way up.
This season, in the Sao Paulo game one of Kaylor's top picks was Green Bay wide receiver Jayden Reed, who caught four passes for 138 yards and a touchdown and rushed for 33 yards and a score, and James Cook, who scored three touchdowns on Thursday Night Football against the Dolphins.
Now, Kaylor has turned his attention to 49ers vs. Seahawks on Thursday Night Football in Week 6 and locked in his top daily Fantasy football picks. You can only see his picks and analysis at SportsLine.
Top NFL DFS picks for Seahawks vs. 49ers
One of Kaylor's top NFL DFS picks for Thursday Night Football is 49ers wide receiver Deebo Samuel. Before San Francisco traded for Christian McCaffrey, Samuel was the jack-of-all-trades uber-versatile weapon in the offense. Samuel had 1,770 total yards (1,405 receiving and 365 rushing) rushing in 2021, the third-most in the NFL. The 28-year-old missed Week 3 with a hamstring injury, but now that he's approaching a month since first suffering the injury, the 49ers should have a healthier Samuel and could look to utilize his skills in different ways with better health.
Although it's only Week 6, the 49ers certainly don't want to fall two games behind the Seahawks and lose the opportunity to secure the tiebreaker, so expect head coach Kyle Shanahan to be creative with his offensive play calls. Creativity favors Samuel and the six-year receiver has had some of his most dominant games against the Seahawks over his career. Samuel has more than 100 receiving yards in five of seven career games against Seattle and Kaylor expects another big performance as the 49ers look to avoid back-to-back losses.
Kaylor is also targeting Seahawks wide receiver Jaxon Smith-Njigba, who had his first touchdown of the season last week and has 19 targets over his last two games. The second-year receiver has played more than 80% of snaps the last four weeks, including at least 88% in two of his last three games. He only played 80% of snaps once last season as it's clear new offensive coordinator Ryan Grubb is looking to get Smith-Njigba's speed and big-play ability on the field more often. Smith-Njigba was the first receiver selected in the 2023 NFL Draft (No. 20 overall) and is averaging more than two more receptions per game (5.8) this season than he did last year (3.7).
Smith-Njigba had six receptions on 10 targets for 66 yards over his two games against the 49ers last season. However, this is his first matchup in his expanded role under Grubb and the 49ers are allowing the 24th-most yards per reception this season. Smith-Njigba doesn't come at a huge price and after scoring his first touchdown of the season last week, Kaylor believes he'll return value for Thursday Night Football NFL DFS lineups. See who else Kaylor likes right here.
How to set 49ers vs. Seahawks NFL DFS lineups, player pool
Kaylor is also targeting another undervalued player who could explode for huge numbers in Seahawks vs. 49ers. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of Kaylor's NFL DFS picks, at SportsLine.
So who is Jimmie Kaylor including in his optimal NFL DFS lineups for Thursday Night Football, and which under-the-radar NFL DFS picks offer huge value? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice, and stacks, all from a DFS expert who won a prestigious millionaire maker tournament, and find out.
