Saquon Barkley and the New York Giants will take on Josh Allen and the Buffalo Bills at 1 p.m. ET on Sunday at MetLife Stadium. The Bills earned an impressive come from behind victory over the New York Jets in Week 1, while the Giants suffered an 18-point loss on the road to the Dallas Cowboys. Despite winning just one of their last five games against the Giants, the Bills enter Sunday's matchup as a two-point favorite according to the latest Bills vs. Giants odds. The over-under, or total number of points Vegas thinks will be scored, is set at 44. Before you make any Bills vs. Giants picks and NFL predictions for Week 2, you'll want to see what the SportsLine Projection Model is saying.

This model, which simulates every NFL game 10,000 times, is up over $7,000 for $100 players on its top-rated NFL picks since its inception four years ago. It has nailed its recent top-rated NFL picks, entering Week 2 of the 2019 NFL season on a sizzling 17-6 run that dates back to last season. It's also on a strong 79-49 roll on top-rated NFL picks that dates back to the 2017 season.

The model ranked in the Top 10 on NFLPickWatch.com for the third straight year on straight-up NFL picks and beat over 96 percent of CBS Sports office pool players. Anyone who has followed it is way up. 

Now, the model has dialed in on Bills vs. Giants. We can tell you it is leaning under, and it also says one side of the spread cashes in nearly 60 percent of simulations. That pick is only available at SportsLine.

The model knows the Giants want to lean heavily on the ground game. However, in their Week 1 loss at Dallas, the Giants only gave Barkley 11 carries. Despite receiving a low number of touches, Barkley seemed to pick up where he left off last season, finishing the NFC East battle averaging over 10 yards per carry. Last season, the former Penn State standout finished the year with 1,307 rushing yards, 721 receiving yards and 15 total touchdowns. 

Tight end Evan Engram was a bright spot for New York's offense against Dallas. In fact, Engram hauled in 11 passes for 116 yards and a score. Engram plans to be a major factor again in New York's aerial attack now that wide receiver Sterling Shepard has been ruled out of Sunday's game due to a concussion.

But just because New York features a lot of talent on the offensive side of the ball doesn't guarantee it will cover the Bills vs. Giants spread on Sunday.

That's because the Bills feature an extremely suffocating defense. Last week against the Jets, Buffalo's stingy defense allowed Sam Darnold to throw for just 175 yards and corralled Le'Veon Bell all game, allowing him to rush for just 60 yards on 17 carries. 

Allen, the Bills' second year quarterback out of Wyoming, also played well when it mattered most. In the fourth quarter against the Jets, Allen completed five-of-seven passes for 77 yards and a touchdown. He's a dynamic playmaker who has proven to have big play potential every time he touches the ball. 

So who wins Bills vs. Giants? And which side of the spread can you bank on in almost 60 percent of simulations? Visit SportsLine now to see which side of the Bills vs. Giants spread to jump on Sunday, all from the advanced model that is up more than $7,000 on its top-rated NFL picks, and find out.