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Week 10 of the 2023 NFL season gets underway when the Carolina Panthers visit the Chicago Bears on Thursday Night Football. Carolina (1-7), which is coming off a 27-13 home loss to Indianapolis, is 0-4 on the road this year and lost its previous five regular-season games in Chicago. The Bears (2-7) ended their 10-game home losing streak with a 30-12 triumph over Las Vegas in Week 7, but enter TNF having lost back-to-back road contests against the Los Angeles Chargers and New Orleans. 

Kickoff from Soldier Field is set for 8:15 p.m. ET. Chicago is a 3.5-point favorite in the latest Bears vs. Panthers odds, while the over/under for total points scored is 38. Before making any Panthers vs. Bears picks of your own, you need to see the NFL predictions and betting advice from SportsLine's Advanced Computer Model

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 10 of the 2023 NFL season on an incredible 174-123 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 28-15 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Bears vs. Panthers and just locked in its picks and Thursday Night Football predictions. You can head to SportsLine now to see the model's picks. Here are several NFL odds and betting lines for Panthers vs. Bears: 

  • Bears vs. Panthers spread: Chicago -3.5
  • Bears vs. Panthers over/under: 38 points 
  • Bears vs. Panthers money line: Chicago -163, Carolina +138
  • CHI: Bears failed to cover the spread the only previous time they were favorites this year
  • CAR: Panthers are 1-6-1 against the spread this season
  • Bears vs. Panthers picks: See picks at SportsLine

Why the Bears can cover

With Justin Fields not ready to return from the dislocated thumb he suffered against Minnesota in Week 6, Tyson Bagent will make his fourth consecutive start. The 23-year-old rookie performed well in his first home outing, leading three touchdown drives in the triumph over the Raiders. Bagent completed 21-of-29 pass attempts for 162 yards and connected with running back D'Onta Foreman for a 5-yard score in the third quarter to give the Bears a 21-3 lead.

Bagent came up with the first multi-TD performance of his career last week as he made a pair of touchdown tosses to tight end Cole Kmet in Chicago's 24-17 loss at New Orleans. He was second on the club in that contest with 70 yards on the ground and is tied for the team lead this season with two rushing scores. On the other side of the ball, the Bears have been strong against the run as they have allowed the fewest yards per carry (3.3) in the NFL this year. See which team to pick here.

Why the Panthers can cover

Carolina is facing a Bears defense that ranks 28th in the NFL against the pass (256.9 yards permitted) and points allowed (26.9). The Panthers will be without receiver DJ Chark, who scored the team's lone touchdown last week, meaning Adam Thielen's workload could increase. The 33-year-old Thielen made only five catches against Indianapolis but is sixth in the league with 62 receptions, eight fewer than he racked up with Minnesota last season.

Thielen is Carolina's leading receiver with 610 yards and four TD catches as he marches toward his third career 1,000-yard season and first since 2018, when he set personal-bests with 113 receptions and 1,373 yards. Rookie Jonathan Mingo, who is third on the Panthers with 200 receiving yards, also could be targeted more often on Thursday. The 22-year-old wideout made just one catch for five yards against the Colts but hauled in four passes for a career-high 62 yards versus Houston a week earlier. See which team to pick here.

How to make Bears vs. Panthers picks on TNF

SportsLine's model is leaning Over the point total, calling for 42 combined points. The model also says one side of the spread has all the value. You can only see the model's TNF picks at SportsLine.

So who wins Panthers vs. Bears on Thursday Night Football, and which side of the spread has all the value? Visit SportsLine now to see which side of the Panthers vs. Bears spread you need to jump on, all from the model on a 174-123 roll on NFL picks, and find out.