Colts' Trey Sermon: Set for Week 6 lead role

Sermon is poised to lead the Colts backfield Sunday against the Titans, as Jonathan Taylor (ankle) was ruled out Friday.

Taylor will miss a second consecutive game. In Taylor's absence against the Jaguars in Week 5, Sermon racked up 63 yards from scrimmage and a touchdown on 10 carries and six catches. Sermon's 16 touches were double the total that fellow RB Tyler Goodson saw, and they could be headed for a similar distribution against Tennessee.