The Oregon Ducks and Washington Huskies have a recent history of high-stakes Pac-12 contests and they are set for another one Saturday. Kickoff is set for 3:30 p.m. ET from Husky Stadium. These clubs historically battle for the North Division title and each has two conference championships this decade. The Huskies overcame a 30-27 overtime loss at Oregon last year to win their second Pac-12 title in the past three years. But the Ducks (5-1, 3-0), who are in first place, appear to be in commanding position to represent the North in this year's title game and a win Saturday would all but seal their fate. The Huskies (5-2, 2-2) can stay alive with the upset. The Ducks are 3-point favorites and the over-under for total points scored is 48.5 in the latest Oregon vs. Washington odds. Before you make any Oregon vs. Washington picks, you need to hear what SportsLine senior analyst Josh Nagel has to say.

A Nevada-based handicapper with more than 20 years of experience in the sports wagering industry, Nagel specializes in collegiate athletics and was SportsLine's top college football analyst last year. He is in the midst of another strong season for SportsLine members. What's more, he has a keen sense for the tendencies of these Pac-12 programs, and won four straight against the spread picks on games involving Washington. 

Two weeks ago, Nagel told SportsLine members that Washington (-14.5) would struggle against a rebuilding Stanford club in what his historically a tight and physical contest. The Cardinal dominated from the outset and pulled the 23-13 outright upset. Anyone who followed Nagel's advice picked up another easy winner, and those who have consistently followed him are way up.

Now, he has zeroed in on Oregon vs. Washington from every angle and released another strong against the spread pick that he's only sharing over at SportsLine.

The Ducks must move on without tight end Jacob Breeland, their leading receiver who suffered a season-ending leg injury against Colorado. He had 405 yards with six touchdowns and likely was headed toward All-America honors. The good news is, they have seen other players emerge as reliable targets and newcomers contribute to the fold.

Receiver Jaylon Redd has scored in five straight games and the junior now has 26 catches for 260 yards. Freshman Mycah Pittman recently returned from injury and has seven catches for 100 yards in his first two collegiate games. Nine different players registered catches against Colorado, with five finishing with at least 24 receiving yards as quarterback Justin Herbert spread the ball around. 

Oregon has not allowed an opponent to reach double-digit points since the Week 1 loss to Auburn. Even so, there's no guarantee the Ducks will cover the Washington vs. Oregon spread.

Washington bounced back from the loss to Stanford with a 51-27 victory at Arizona last week. The Huskies trailed 17-13 at the intermission, but took command with a 14-0 burst in the third quarter. Quarterback Jacob Eason had an efficient game, going 15-of-22 for 243 yards and two touchdowns. Salvon Ahmed had 23 carries for 95 yards and three scores. Washington held the Wildcats to 10 second-half points, all of which came in the fourth quarter with the outcome in hand, and forced four turnovers.

Nagel has broken down this matchup from every angle and identified the critical factor that has him all over one side of the spread. He's only sharing it at SportsLine. 

Who wins Oregon vs. Washington? And what critical factor makes one side of the spread a must-back? Visit SportsLine now to see which side of the Oregon vs. Washington spread you should jump on Saturday, all from the seasoned expert who has hit four straight against the spread picks on Washington, and find out.