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The No. 16 Mississippi State Bulldogs will try to extend their three-game winning streak when they face the No. 22 Kentucky Wildcats on Saturday night. Mississippi State suffered a disappointing loss to LSU a month ago, but it has bounced back with a trio of dominant performances. Meanwhile, Kentucky is hoping to snap a two-game losing streak following a 24-14 loss to South Carolina

Kickoff is set for 7:30 p.m. ET. The Bulldogs are favored by 4 points in the latest Kentucky vs. Mississippi State odds from Caesars Sportsbook, while the over/under is set at 49. Before entering any Mississippi State vs. Kentucky picks, you'll want to see the college football predictions from the advanced computer model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Kentucky vs. Mississippi State. You can head to SportsLine to see its picks. Here are several college football odds for Kentucky vs. Mississippi State:

  • Kentucky vs. Mississippi State spread: Kentucky +4
  • Kentucky vs. Mississippi State over/under: 49 points
  • Kentucky vs. Mississippi State picks: See picks here

Why Mississippi State can cover

Mississippi State has put together three extremely impressive performances in a row following its loss to LSU. The Bulldogs have recorded blowout wins over Bowling Green, Texas A&M and Arkansas in consecutive weeks, giving them momentum heading into this game. They are led by junior quarterback Will Rogers, who has thrown for 2,110 yards and 22 touchdowns. 

He completed 31 of 48 passes for 395 yards and three touchdowns against Arkansas, as the team finished with 568 total yards of offense. Kentucky is coming off back-to-back losses, including a shocking loss to South Carolina last week. Mississippi State picked up a 31-17 win over the Wildcats last year. 

Why Kentucky can cover

This game is the epitome of a buy-low, sell-high spot. Kentucky is being discarded following its rough performance against South Carolina, while Mississippi State has looked fantastic in its last three games. However, the Wildcats had either won or covered the spread in five straight games prior to their loss to South Carolina, while Mississippi State was blown out by LSU in its last road game. 

The Bulldogs have a huge showdown at No. 3 Alabama coming up next week, so this is a lookahead spot for them. Kentucky quarterback Will Levis is expected to return from an ankle injury after sitting out last week, which would give his team a major boost. The Wildcats are 11-2 in their last 13 home games and have covered the spread in four of their last five home games against Mississippi State. 

How to make Kentucky vs. Mississippi State picks

The model has simulated Mississippi State vs. Kentucky 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

So who wins Kentucky vs. Mississippi State? And which side of the spread hits in well over 50% of simulations? Visit SportsLine now to see which side of the Mississippi State vs. Kentucky spread you need to jump on Saturday, all from the model that has crushed its college football picks, and find out.