Quarterback Cam Ward and the No. 6 Miami (FL) Hurricanes (6-0) will try to stay on track for a spot in the College Football Playoff when they go on the road to face the Louisville Cardinals (4-2) on Saturday afternoon. Miami has escaped with narrow wins over Virginia Tech and California in its last two outings, keeping pace with Clemson atop the ACC standings. Louisville snapped a two-game losing streak with a 24-20 win at Virginia last week, scoring the game-winning touchdown with less than two minutes remaining. These teams played a thrilling game last season, as Louisville notched a 38-31 road win as 1-point underdogs.
Kickoff is set for noon ET on Saturday at L&N Federal Credit Union Stadium. Miami is favored by 5 points in the latest Louisville vs. Miami odds, while the over/under is 59.5 points, per SportsLine consensus. Before entering any Miami vs. Louisville picks, you'll want to see the college football predictions from the model at SportsLine.
The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a sizzling 12-5 on all top-rated picks for sports betting over the past three weeks of this season. Anyone who has followed it at sports betting apps has seen strong returns.
The model has set its sights on Miami (FL)-Louisville. You can head to SportsLine to see its picks. Here are several college football betting lines for the game:
- Louisville vs. Miami spread: Miami -5
- Louisville vs. Miami over/under: 59.5 points
- Louisville vs. Miami money line: Miami -201, Louisville +165
- Louisville vs. Miami picks: See picks here
- Louisville vs. Miami streaming: FuboTV (Try for free)
Why Louisville can cover
Louisville went on the road and picked up a 38-31 win at Miami last season, giving the Cardinals four wins in the past six meetings between these teams. They are coming off a 24-20 win over Virginia last week, as senior quarterback Tyler Shough threw a game-winning touchdown pass to freshman tight end Jamari Johnson with 1:55 remaining. Shough started his career at Oregon, sitting behind Chargers quarterback Justin Herbert on the depth chart.
Shough led the Ducks to the Pac-12 title in 2020 before transferring to Texas Tech and now Louisville for his seventh college season. He has completed 63.4% of his passes for 1,674 yards and 14 touchdowns, while running back Donald Chaney has 110 rushing yards for Louisville after spending his first four seasons at Miami. True freshman running back Isaac Brown leads the Cardinals in rushing yards (508), yards per carry (8.6) and total scrimmage yards (600). See which team to pick here.
Why Miami can cover
Miami held a players-only meeting earlier this week, suggesting that the Hurricanes wanted to re-focus following a pair of close calls. They have scored at least 38 points in every game this season, and Louisville will have their full attention following last year's loss. Ward, a top Heisman contender, helped Miami rally from a 10-point deficit in the fourth quarter against Virginia Tech and a 20-point deficit against California.
Ward leads the country in passing yards per game (369.8), while wide receiver Xavier Restrepo leads the ACC in receiving yards (585). The Hurricanes will have star left tackle Jalen Rivers available on Saturday for the first time since the season opener, giving their offensive line a boost. Miami has covered the spread in four of its last five road games, while Louisville has only covered the spread three times in its last nine games. See which team to pick here.
How to make Louisville vs. Miami picks
The model has simulated Miami vs. Louisville 10,000 times and the results are in. The model is leaning Over, and it's also generated a point-spread pick that is hitting in over 50% of simulations. You can only see the pick at SportsLine.
So who wins Louisville vs. Miami, and which side of the spread is hitting over 50% of the time? Visit SportsLine now to see which side of the Miami vs. Louisville spread to jump on, all from the advanced computer model that's up well over $2,000 on its top-rated college football spread picks since its inception, and find out.
