The Louisville Cardinals (4-2) will take aim at a signature win on Saturday afternoon when they host Heisman contender Cam Ward and the No. 6 Miami Hurricanes (6-0). Louisville snapped a two-game losing streak with a 24-20 win at Virginia last week, and this will be its final home game until Nov. 23. Miami cruised to blowout wins in its first four games of the season before needing to erase double-digit deficits against Virginia Tech and California. The Hurricanes join Clemson, Pittsburgh and SMU as the remaining teams unbeaten in ACC play.
Kickoff is set for noon ET at L&N Federal Credit Union Stadium in Louisville. The Hurricanes are 5.5-point favorites, per SportsLine consensus, in the latest Louisville vs. Miami odds. The over/under for total points is 61. Before entering any Miami vs. Louisville picks, you'll want to see the college football predictions from the model at SportsLine.
The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a sizzling 12-5 on all top-rated picks for sports betting over the past three weeks of this season. Anyone who has followed it at sports betting apps has seen strong returns.
The model has set its sights on Miami vs. Louisville. You can head to SportsLine to see its picks. Here are several college football betting lines for the game:
- Louisville vs. Miami spread: Miami -5.5
- Louisville vs. Miami over/under: 61 points
- Louisville vs. Miami money line: Miami -211, Louisville +172
- Louisville vs. Miami picks: See picks here
- Louisville vs. Miami streaming: FuboTV (Try for free)
Why Louisville can cover
While Miami was flat-out dominant in its first four games this season, the Hurricanes have shown signs of regression over their last two outings. They survived a late Hail Mary against Virginia Tech that was overturned by replay before needing to erase a 20-point deficit against California. Miami was a double-digit favorite in both of those games, but it never came close to covering in either contest.
Louisville has shown up for its biggest games under head coach Jeff Brohm, covering the spread at a 2-1-1 clip in four games against ranked opponents over the last two seasons. The Cardinals are averaging more than 36 points per game while allowing fewer than 20, and quarterback Tyler Shough is a seventh-year senior. He has an elite wide receiver at his disposal in Ja'Corey Brooks, who is one of the top wideouts in the ACC with 30 receptions for 572 yards and six touchdowns. See which team to pick here.
Why Miami can cover
Miami held a players-only meeting earlier this week, suggesting that the Hurricanes wanted to re-focus following a pair of close calls. They have scored at least 38 points in every game this season, and Louisville will have their full attention following last year's loss. Ward, a top Heisman contender, helped Miami rally from a 10-point deficit in the fourth quarter against Virginia Tech and a 20-point deficit against California.
Ward leads the country in passing yards per game (369.8), while wide receiver Xavier Restrepo leads the ACC in receiving yards (585). The Hurricanes will have star left tackle Jalen Rivers available on Saturday for the first time since the season opener, giving their offensive line a boost. Miami has covered the spread in four of its last five road games, while Louisville has only covered the spread three times in its last nine games. See which team to pick here.
How to make Louisville vs. Miami picks
The model has simulated Miami vs. Louisville 10,000 times and the results are in. The model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.
So who wins Louisville vs. Miami, and which side of the spread is hitting well over 50% of the time? Visit SportsLine now to see which side of the Miami vs. Louisville spread to jump on, all from the advanced computer model that's up well over $2,000 on its top-rated college football spread picks since its inception, and find out.
