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The fourth-ranked Clemson will be looking to begin another ACC title run when the Tigers face the Georgia Tech Yellow Jackets at Mercedes-Benz Stadium in Atlanta on Monday night. The Tigers failed to win the conference last year, but they have two national titles and two runner-up finishes since 2015, and they are the preseason pick to win the ACC this year. Georgia Tech, meanwhile, is coming off a 3-9 campaign, including a 2-6 mark in the ACC.

Kickoff from Atlanta is set for 8 p.m. ET. The Tigers are 24-point favorites in the latest Clemson vs. Georgia Tech odds from Caesars Sportsbook, while the over/under for total points scored is 51. Before making any Georgia Tech vs. Clemson picks, be sure to see the college football predictions and betting advice from SportsLine's proven computer model

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,600 for $100 players on its top-rated college football picks against the spread. It enters Week 1 of the 2022 college football season on a 45-32 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, the model has locked in on on Clemson vs. Georgia Tech and just locked in its picks and CFB predictions. You can head to SportsLine now to see the model's picks. Here are several college football odds and betting lines for Georgia Tech vs. Clemson:

  • Georgia Tech vs. Clemson spread: Clemson -24
  • Georgia Tech vs. Clemson over/under: 51 points
  • Georgia Tech vs. Clemson money line: Tigers -3500, Yellow Jackets +1350
  • CLEM: The Tigers are 5-1 ATS in their last six games overall
  • GT: The Yellow Jackets are 5-1-1 ATS in their last seven neutral site games
  • Georgia Tech vs. Clemson picks: See picks at SportsLine

Why Clemson can cover

Clemson should have one of the best defenses in the country again this season after ranking second nationally in scoring defense and eighth in yards allowed per game. The Tigers bring back seven starters from that unit, including three players who are on the watch list for the Lombardi and Bednarik awards. They have momentum entering the 2022 season after winning six consecutive games down the stretch last year, covering the spread in five of those victories.

Clemens's offense is expected to show improvement under quarterback DJ Uiagalelei, who had 2,246 passing yards and nine touchdowns last year. He is facing a Georgia Tech team that has struggled under head coach Geoff Collins, winning just three games in three straight seasons. The Yellow Jackets lost star running back Jahmyr Gibbs to the transfer portal, so they are going to have trouble getting anything going against Clemson's defense. Plus, the Tigers have won 36 of their last 38 conference games. 

Why Georgia Tech can cover

Senior receiver Malachi Carter looks to embrace the role of being the No. 1 target in this offense. Carter is a smooth route runner who owns strong hands. The Georgia native does a nice job at targeting deep passes and is a legit threat downfield. Last season, he led the team in catches (37) and receiving yards (489) with 13.2 yards per reception.

On the defensive side, senior linebacker Ayinde Eley is a force in the middle of the defense for the Yellow Jackets. Eley is a big hitter with great lateral quickness. He uses his long arms as an asset in the passing game to defend running backs and tight ends. This also helps him wrap up ball carriers easily. The Maryland native was second on the team in total tackles (88). 

How to make Clemson vs. Georgia Tech picks

SportsLine's model is leaning Over on the point total, projecting the teams to combine for 52 points. The model also says one side of the spread hits in well over 50% of simulations. You can only see the model's pick at SportsLine.

So who wins Clemson vs. Georgia Tech? And which side of the spread hits in well over 50% of simulations? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that has crushed its college football picks, and find out.