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The Air Force Falcons look to begin the season 3-0 for the first time since 2016 when they take on the Wyoming Cowboys in a Mountain West Conference Mountain Division opener on Friday. The game can be seen on CBS Sports Network. The Falcons are coming off a dominating performance in a 41-10 thumping of Colorado in Week 2, while the Cowboys (2-1) rolled to a 33-10 win over Northern Colorado. This will be the 60th meeting all-time between the teams, with Air Force holding a 30-26-3 edge in the series. The Falcons have also won the last two games against the Cowboys. Air Force led the nation in rushing offense in 2021, averaging 328.2 yards per game, while Wyoming averaged 211.7 rushing yards, 20th-best in the country.

Kickoff from War Memorial Stadium in Laramie, Wyoming, is set for 8 p.m. ET. The Falcons are favored by 15 points in the latest Air Force vs. Wyoming odds from Caesars Sportsbook, while the over-under for total points scored is 46.5. Before making any Wyoming vs. Air Force picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,400 for $100 players on its top-rated college football picks against the spread. It enters Week 3 of the 2022 college football season on a 50-41 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Air Force vs. Wyoming and just locked in its picks and CFB predictions. You can visit SportsLine now to see the model's picks. Here are the college football odds and betting lines and trends for Wyoming vs. Air Force:

  • Air Force vs. Wyoming spread: Air Force -16.5
  • Air Force vs. Wyoming over/under: 47 points 
  • Air Force vs. Wyoming money line: Air Force -800, Wyoming +550
  • AFA: The Falcons are 6-0 against the spread in their last six games 
  • WYO: The Cowboys are 8-1 ATS in their last nine home games against a team with a winning road record 
  • Air Force vs. Wyoming picks: See picks here

Why Air Force can cover

Air Force leads the nation in rushing with a 508.5 average. The Falcons rushed for 582 yards in the season opener vs. Northern Iowa, which is the sixth most in school history and the most since rushing for 595 against Tennessee State in 2011. Air Force rushed for 435 yards vs. Colorado. The Falcons lead the nation by 206.5 yards per game, led by senior running back Brad Roberts, who has carried 32 times for 288 yards (9.0 average) and four touchdowns.

Senior quarterback Haaziq Daniels is a dual threat on offense. He has completed just 4 of 11 passes for 117 yards (10.6 average) and one touchdown. Daniels has also rushed 21 times for 136 yards (6.5 average) and two touchdowns. He is the only FBS player to hold school records for both longest run and pass. Daniels set both last season, setting the Air Force record for longest run with a 94-yard dash for a touchdown against Florida Atlantic. He set the passing record with a 92-yard touchdown toss to Brandon Lewis vs. Colorado State.

Why Wyoming can cover 

Wyoming junior quarterback Andrew Peasley was selected as the Mountain West Conference Offensive Player of the Week for his performance in leading Wyoming to a 40-37 double-overtime home win over Tulsa two weeks ago and has played well since a tough performance at Illinois. Against Tulsa, the Cowboys trailed 34-24 with 14:54 remaining in regulation when Peasley guided them to two scoring drives to send the game into overtime. He finished the game completing 20 of 30 passes (66.7%) for 256 yards and two touchdowns. Last week against Northern Colorado, Peasley completed 19 of 30 passes (63.3%) for 144 yards in a 33-10 victory.

Wyoming also boasts a strong kicking game, led by sophomore kicker John Hoyland, who earned Mountain West Special Teams Player of the Week honors two weeks ago. Hoyland tied a career long with a 55-yard field goal in the fourth quarter to pull the Cowboys within a touchdown vs. Tulsa. He then kicked a 25-yard field goal in the first overtime before winning the game with a 30-yarder. He was also 4-for-4 on PATs, and had six touchbacks on seven kickoff attempts. Last week, Hoyland was 4-for-4 on field goals and 3-for-3 on extra points.

How to make Air Force vs. Wyoming picks

SportsLine's model is leaning Over on the total, projecting 50 combined points. It has also generated an against-the-spread pick that cashes in almost 60% of simulations. You can only see the model's pick at SportsLine

So who wins Air Force vs. Wyoming? And which side of the spread cashes in almost 60% of simulations? Visit SportsLine now to see which side of the Air Force vs. Wyoming spread to jump on, all from the advanced model that finished the past six-plus years up nearly $3,400 on its FBS college football picks, and find out.