No. 2 Virginia (27-2, 15-2) wraps up its regular-season ACC campaign against Louisville (19-11, 10-7) at 4 p.m. ET on Saturday. Virginia is looking to bolster its case for the top overall seed in the 2019 NCAA Tournament, while the Cardinals are hoping to find themselves on the right side of the bubble come Selection Sunday. The Cavaliers are favored by 13 points in the latest Virginia vs. Louisville odds, while the over-under for total points scored is 126. Before locking in any Virginia vs. Louisville picks of your own, be sure to check out the college basketball predictions from SportsLine's proven computer model. 

This model, which simulates every game 10,000 times, has raked in the winnings for those following its picks. Over the past two years, the SportsLine Projection Model has returned nearly $4,200 to $100 players on its top-rated college basketball picks. It also entered Week 18 of the 2018-19 college basketball season on a strong 111-87 run against the spread. Anyone who has followed it is way up.

Now it has analyzed all relevant data and crunched the numbers for Virginia vs. Louisville. We can tell you it's leaning over, and it also says one side of the spread has all the value. That pick is only available at SportsLine. 

The model has taken into account that Virginia is in play for the No. 1 overall seed in the 2019 NCAA Tournament thanks to an impressive season that has includes a seven-game winning streak as it heads into the final regular-season matchup. Virginia's only two losses on have come to Duke.

The Cavaliers are best known for their top-ranked defense that gives up just 54.1 points per game. They held Louisville to just 52 in their first meeting, a 12-point victory for UVA. But they're strong on the other end of the floor as well, averaging 72.1 points per contest. They've been even better than that in their last three, scoring 77.6 points per game during that span. 

But a balanced attack doesn't guarantee the Cavaliers will be able to cover the Virginia vs. Louisville spread.

The model also knows Louisville has limped down the stretch a bit, but has momentum after knocking off Notre Dame by 14 earlier this week. And the Cardinals have shown they can beat some of the best teams in the nation, as evidenced by wins over North Carolina and Virginia Tech

Louisville, currently projected as a No. 7 seed in the 2019 NCAA Tournament by CBS Sports expert Jerry Palm, also has a winning record against the spread both on the road and as an underdog. 

Who wins Louisville vs. Virginia? And which side of the spread has all the value? Visit SportsLine now to find out which side of the Louisville vs. Virginia spread you need to jump on, all from the model that has crushed college hoops, and find out.