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The Michigan State Spartans and the No. 3 Purdue Boilermakers face off in a Big Ten battle on MLK Day. Michigan State heads into Monday's matchup with a 12-5 record. Meanwhile, the Boilermakers own a 16-1 record. Michigan State leads the all-time series 26-17. However, Purdue won the last contest against the Spartans, 75-70.

Tip-off from the Breslin Center in East Lansing is set for 2:30 p.m. ET. The Boilermakers are 4-point favorites in the latest Purdue vs. Michigan State odds from Caesars Sportsbook, while the over/under for total points scored is 133. Before locking in any Michigan State vs. Purdue picks, be sure to see the college basketball predictions and betting advice from SportsLine's proven computer model.  

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. The model enters Week 11 of the season 41-21 on all-top rated college basketball picks, returning more than $1,200 for $100 players. Anybody who has followed it has seen profitable returns.

Now, the model has set its sights on Purdue vs. Michigan State and just locked in its picks and CBB predictions. You can visit SportsLine now to see the model's picks. Here are the college basketball odds and betting lines for Michigan State vs. Purdue:

  • Purdue vs. Michigan State spread: Boilermakers -4
  • Purdue vs. Michigan State over/under: 133 points 
  • Purdue vs. Michigan State money line: Boilermakers -180, Spartans +155
  • PUR: The Boilermakers are 4-1 ATS in their last five games following an ATS win
  • MSU: The Spartans are 5-1 ATS in their last six games following a straight-up loss
  • Purdue vs. Michigan State picks: See picks at SportsLine

Why Purdue can cover

Guard Fletcher Loyer has a quick release and solid range on his jumpers. Loyer can either create his own shot or knock down jumpers as a catch-and-shoot option. The Indiana native is second on the team with 13.2 points and shoots 36% from 3-point land. He's supplied at least 17 points and four 3-pointers in back-to-back games. On Friday, Loyer tallied a season-high 27 points and six threes. 

Junior center Zach Edey has been a quality shot blocker and alters shots due to his size (7'4, 290 pounds). Edey can dominate in the paint and owns a soft touch around the rim. The Ontario native is 13th in the nation in scoring (21.2 points per game) but first in rebounds per game (13.2). Additionally, he's second in the country in double-doubles (14). On Jan. 8, Edey logged 30 points, 13 rebounds and three blocks against Penn State

Why Michigan State can cover 

Senior guard Tyson Walker is a floor-spacing perimeter threat. Walker has a smooth jumper but can take his defender off the dribble. The New York native averages a team-high 13.9 points, 2.9 assists, and shoots 40% from beyond the arc. He's scored at least 14 points in three of his last four games. On Jan. 3 against Nebraska, Walker had 21 points and knocked down three 3-pointers. 

Senior forward Joey Hauser is a strong and tough player in the frontcourt. Hauser can get a bucket in a variety of ways including from the low post or with a jumper. The Wisconsin native averages 13.6 points and eight rebounds per game. He's registered a double-double in three of his past five outings. Hauser finished with 11 points and 11 boards in Friday's loss against Illinois

How to make Michigan State vs. Purdue picks

SportsLine's model is leaning Over on the total, projecting 141 combined points. It has also generated an against the spread pick that hits in well over 50% of simulations. You can only get the model's pick at SportsLine

So who wins Purdue vs. Michigan State? And which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is 41-21 on its top-rated college basketball picks this season, and find out.