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The top-seeded Purdue Boilermakers are looking for back-to-back conference tournament championships as they meet the eighth-seeded Michigan State Spartans in a 2024 Big Ten Tournament quarterfinal matchup on Friday. The Boilermakers (28-3, 17-3 Big Ten), who also won the regular-season title, have won the past four meetings with Michigan State, including an 80-74 win on March 2. The Spartans (19-13, 10-10 Big Ten), who is 2-2 on neutral courts, have won four of five Big Ten Tournament meetings against Purdue. The Boilermakers own a 76-56 edge in the all-time series.

The game from the Target Center in Minneapolis will tip off at noon ET. Michigan State is averaging 73.4 points per game, while Purdue averages 84.2. The Boilermakers are 7.5-point favorites in the latest Michigan State vs. Purdue odds from SportsLine consensus, while the over/under for total points scored is 142.5. Before making any Purdue vs. Michigan State picks, be sure to see the college basketball predictions and betting advice from the proven SportsLine Projection Model.

The model simulates every Division I college basketball game 10,000 times. It enters 2024 conference championship week on a 145-104 roll on all top-rated college basketball picks dating back to last season, returning more than $1,700 for $100 players. It also has a strong 28-18 (+820) record on top-rated spread picks this season. Anyone following has seen huge returns.

Now, the model has set its sights on Purdue vs. Michigan State and revealed its CBB picks and predictions. You can head to SportsLine now to see the model's picks. Here are several college basketball odds and trends for Michigan State vs. Purdue:

  • Purdue vs. Michigan State spread: Purdue -7.5
  • Purdue vs. Michigan State over/under: 142.5 points
  • Purdue vs. Michigan State money line: Michigan State +276, Purdue -357
  • MSU: The Spartans have won six Big Ten Conference Tournament titles
  • PUR: Boilermakers coach Matt Painter has 17 wins against Michigan State, the most victories against Spartans coach Tom Izzo
  • Purdue vs. Michigan State picks: See picks at SportsLine

Why Purdue can cover

Zach Edey is the headliner for Purdue, but the Boilermakers have a deep group of scorers. Senior guard Lance Jones has been a big part of the Boilermakers' success on offense, and is one of four players averaging 10 or more points per game. He is coming off a 13-point, two-rebound effort in the win over Wisconsin on Sunday. He is averaging 10 points and 2.5 rebounds over the past two games, and needs just one more point to reach 1,900 for his career. In 31 games, all starts, he is averaging 12.4 points, 2.7 rebounds, 2.1 assists and 1.3 steals in 28.2 minutes.

Sophomore Fletcher Loyer had a big game against Wisconsin on Sunday, scoring 15 points, grabbing five rebounds and adding four assists. He had 16 points, five assists and three boards in a 77-71 win at 12th-ranked Illinois on March 5. In the last meeting against Michigan State, Loyer scored 15 points and added three assists. In 31 games, all starts, he is averaging 10.6 points, 2.1 rebounds and 1.9 assists. See which team to pick here

Why Michigan State can cover

Senior guard Tyson Walker has been red hot of late. He poured in 15 points, while adding four assists and three rebounds in Thursday's win over Minnesota. He had 30 points and three assists in a 65-64 loss at Indiana on Sunday. In the lone meeting against Purdue this season, he scored 14 points, while adding seven rebounds and four assists. In 30 games, all starts, Walker is averaging 18.4 points, three assists, 2.9 rebounds and 1.9 steals in 32.8 minutes.

Senior forward Malik Hall finished with nine points in the win over the Gophers on Thursday. In 31 games, including 30 starts, he is averaging 12.7 points, 5.7 rebounds and two assists in 28.6 minutes. He scored 15 points and grabbed 17 rebounds in a 53-49 win over Northwestern on March 6. His best game was a 29-point and 10-rebound performance in an 80-72 win at Penn State on Feb. 14. See which team to pick here.

How to make Michigan State vs. Purdue picks

SportsLine's model is leaning Over on the point total, projecting the teams to combine for 147 points. The model also says one side of the spread hits nearly 60% of the time. You can only get the model's pick at SportsLine

So who wins Purdue vs. Michigan State, and which side of the spread hits nearly 60% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that has returned more than $1,700 on its college basketball picks this season, and find out.