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Starting pitcher Seth Lugo put together an impressive 2023 campaign, going 8-7 with a 3.57 ERA across 26 starts for San Diego. He has been even better so far this season, tallying a 6-1 record with a brilliant 1.66 ERA in his first season with Kansas City. Lugo has a favorable matchup against Oakland on Saturday night, which is why he is among the most expensive pitchers in the MLB DFS player pool on sites like DraftKings and FanDuel. Should you include him in your MLB DFS lineups?

Some of the league's best offenses will also be in action during Saturday's MLB DFS main slate, including the Braves and Dodgers. Designated hitter Shohei Ohtani has already blasted 13 home runs this season, but should you tie up a large portion of your bankroll on him with your MLB DFS strategy? Before locking in any MLB DFS picks for Saturday, be sure to check out the MLB DFS advice, strategy and projections from SportsLine daily Fantasy expert Mike McClure.

McClure is a daily Fantasy pro who has won more than $2 million in his career. And when it comes to daily Fantasy baseball, McClure is at his best. Recognized in the book "Fantasy Football (and Baseball) for Smart People: How to Turn Your Hobby into a Fortune" as a top MLB DFS player, McClure's proprietary projection model simulates each game 10,000 times, taking factors such as matchups and recent results into account. This allows him to find the best values on every site.

On Thursday, McClure highlighted Rays OF Josh Lowe as part of his lineup core on FanDuel. The result: Lowe hit a home run and recorded two RBI, returning 25.2 points on FanDuel. Anybody who included him in their lineups was well on the way to a profitable day.

Now, with the 2024 MLB season rolling, McClure has locked in his top MLB daily Fantasy picks for Saturday, May 18. You can head to SportsLine now to see them

McClure's top MLB DFS picks for Saturday 

One of McClure's top MLB DFS picks for Saturday is Royals shortstop Bobby Witt Jr. at $4,300 on FanDuel and $6,400 on DraftKings. Witt enters Saturday's matchup pacing towards a career batting high average (.291), slugging percentage (.497) and OPS (.852). He has five home runs and 15 stolen bases.

Witt has done virtually all his damage against right-handed pitching, which is what he'll see Saturday in Athletics starter Ross Stripling. Stripling is 1-7 with a 4.98 ERA and his fastball velocity and strikeout rate have been among the lowest in the league thus far, giving Witt a chance to return value despite his high DFS prices. 

McClure is also also targeting Red Sox outfielder Jarren Duran ($3,300 on FanDuel, $4,500 on DraftKings), who has a .937 OPS this month and has six hits in his last three games. He takes on the Cardinals and a struggling Miles Mikolas, who has a 6.75 ERA in three starts this month. See McClure's full MLB DFS player pool at SportsLine.

How to set your MLB DFS lineups for May 18, 2024

McClure is also targeting an undervalued player who is set to explode for huge numbers on Saturday. The stars are aligning for him to return tournament-winning value and he comes at a price that won't break the bank. You can only see who it is, and get the rest of McClure's MLB DFS picks, here.

So what are the top MLB DFS picks for Saturday? Visit SportsLine now to see DFS millionaire Mike McClure's complete player pool and picks for FanDuel and DraftKings, all from the DFS expert who has won more than $2 million.